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AIDSVAX® Program:  Current Trials

GSID serves the manufacturing and product sponsor for the AIDSVAX® B/E vaccine, which continues to be used in a number of HIV vaccine trials around the world. The following table represents the current and planned trials:

Study Protocol
Phase
Study Location
Clinical Trial Sponsor
Priming Vaccine
Study Status
RV 305
2
Thailand
US Surgeon General / Dept. of the Army
Sanofi Pasteur ALVAC vCP1521
Completed
RV 305A
2
Thailand
US Surgeon General / Dept. of the Army
AIDSVAX B/E boost only
Completed
RV 306
2
Thailand
US Surgeon General / Dept. of the Army
Sanofi Pasteur ALVAC vCP1521
Completed
RV 328
2
Thailand
US Surgeon General / Dept. of the Army
None / AIDSVAX B/E alone
Completed
HVTN 096/EV04
1
Switzerland
EuroVacc Foundation
EuroVacc NYVAC HIV-PT1, NYVAC HIV-PT4, IPPOX DNA-HIV-PT123
Completed*
HVTN 097
1b
Republic of South Africa
NIH/NIAID/DAIDS
Sanofi Pasteur ALVAC vCP1521
Completed*
HVTN 105
1b
USA
NIH/NIAID/DAIDS
iPox DNA-HIV-PT123
Completed*
HVTN 110
1
USA
PaxVax Inc.
PaxVax Ad4 mgag/Env C150
Completed
HVTN 114
1
USA / Peru
NIH/NIAID/DAIDS
GeoVax MVA/HIV62B
Ongoing
HVTN121
1
USA
NIH/NIAID/DAIDS
AIDSVAX B/E alone
In Planning
HVTN 126
1b
Republic of South Africa
NIH/NIAID/DAIDS
Late boost comparison with 1086.C w/alum
In Planning
PXVX-HIV-100-001
1b
USA
PaxVax Inc.
PaxVax Ad4 mgag/Env C150
Ongoing
EV06
1
Uganda
EuroVacc Foundation
IPPOX DNA-HIV-PT123
Completed*
EV07 
1
Uganda
EuroVacc Foundation
IPPOX DNA-HIV-PT123
Ongoing
* Publications pending
Study Status as of June 1, 2017

 


Additional Resources

  • AIDSVAX® Program: Overview
  • VaxGen Trials
  • RV144 Trials
  • Current Trials
  • AIDSVAX® Collaborators




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